搜索结果: 'methocult media formulations for human hematopoietic cells serum containing'

36:48

线上讲座
Applications of the Hematopoietic CFU Assay in Toxicity Testing

发布日期: 01/17/2020
1:31

视频
Human Primary Cells - Get the Cells You Need from STEMCELL Technologies

发布日期: 12/01/2023
产品手册
AggreWell™ for Spheroids

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品牌：

AggreWell

产品号#：

07010

27215

27250

27845

27945

27840

27865

27940

27965

34811

34815

34850

34821

34825

34860

34421

34425

34460

34411

34415

34450

产品名：

抗粘附冲洗液

37µm可逆滤筛，小 (15 mL)

37µm可逆滤筛，大 (50 mL)

AggreWell™ 800 24孔板，1个

AggreWell™ 800 24孔板，5个

AggreWell™ 800 24孔板启动套装

AggreWell™ 800 6孔板，1个

AggreWell™ 800 6孔板，5个

AggreWell™ 800 6孔板启动套装

AggreWell™ 400 6孔板，1个

AggreWell™ 400 6孔板，5个

AggreWell™ 400 6孔板启动套装

AggreWell™ 400 24孔板，1个

AggreWell™400 24孔板，5个

AggreWell™400 24孔板启动套装
科学海报
Measuring Activity in Human Pluripotent Stem Cell-Derived Neural Organoids for Disease Modeling and Drug Discovery

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1:05:46

视频
Modeling Human Neurological Disease with Induced Pluripotent Stem Cells
产品手册
Derive, Expand, and Differentiate Human Skeletal Muscle Progenitor Cells

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MyoCult

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3:41

视频
Cryopreserve Human Peripheral Blood Mononuclear Cells with CryoStor® CS10

发布日期: 11/22/2024
科学海报
A Simple, Reproducible Method to Generate Red Blood Cells From Human Pluripotent Stem Cells

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Conference：

BCREGMED 2020

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Kuroki MM et al. ( 2005) Anticancer Research 25 6A 3733--9

Preparation of human IgG and IgM monoclonal antibodies for MK-1/Ep-CAM by using human immunoglobulin gene-transferred mouse and gene cloning of their variable regions.

For antibody-based therapy of cancer,monoclonal antibodies (mAbs) of human origin are superior to mouse,mouse/human chimeric or humanized mAbs,because of their minimum immunogenicity to humans and their efficient collaboration with human effector cells. In the present study,human mAbs were prepared against a pancarcinoma antigen,MK-1 (Ep-CAM),using a genetically-engineered mouse (KM mouse) that contains the human immunoglobulin genes. Spleen cells from KM mice,immunized with recombinant MK-1,were fused with P3-U1 mouse myeloma cells. Of 44 anti-MK-1 clones analyzed,two were of IgG4 and the others of IgM clones. Although the two IgG4 clones were suggested to recognize the same antigenic determinant or two closely located determinants,their VK regions were encoded by different light-chain genes while their VH sequences were identical. The two IgG4 and one of the IgM clones tested revealed antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity,respectively,against MK-1-expressing cells in vitro,suggesting that these fully human mAbs produced against MK-1 and their V-region genes,which are applicable for the preparation of engineered antibody fragments that may be useful for antibody-based therapy of cancer. View Publication

产品类型：

产品号#：

03800

03801

03802

03803

03804

03805

03806

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ClonaCell™-HY 杂交瘤试剂盒

ClonaCell™-HY Medium

ClonaCell™-HY Medium

ClonaCell™-HY Medium

ClonaCell™-HY Medium

ClonaCell™-HY Medium

ClonaCell™-HY PEG (融合)
36:59:00

视频
Derivation of Metabolically Active Hepatocytes from Human Pluripotent Stem Cells
科学海报
Efficient, Reproducible and High-Throughput-Compatible Protocols for Differentiation of Human Pluripotent Stem Cell Lines Into Kidney Organoids

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Conference：

ISSCR 2019

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产品名：
Lymperi S et al. (FEB 2011) Blood 117 5 1540--9

Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo.

Osteoblasts play a crucial role in the hematopoietic stem cell (HSC) niche; however,an overall increase in their number does not necessarily promote hematopoiesis. Because the activity of osteoblasts and osteoclasts is coordinately regulated,we hypothesized that active bone-resorbing osteoclasts would participate in HSC niche maintenance. Mice treated with bisphosphonates exhibited a decrease in proportion and absolute number of Lin(-)cKit(+)Sca1(+) Flk2(-) (LKS Flk2(-)) and long-term culture-initiating cells in bone marrow (BM). In competitive transplantation assays,the engraftment of treated BM cells was inferior to that of controls,confirming a decrease in HSC numbers. Accordingly,bisphosphonates abolished the HSC increment produced by parathyroid hormone. In contrast,the number of colony-forming-unit cells in BM was increased. Because a larger fraction of LKS in the BM of treated mice was found in the S/M phase of the cell cycle,osteoclast impairment makes a proportion of HSCs enter the cell cycle and differentiate. To prove that HSC impairment was a consequence of niche manipulation,a group of mice was treated with bisphosphonates and then subjected to BM transplantation from untreated donors. Treated recipient mice experienced a delayed hematopoietic recovery compared with untreated controls. Our findings demonstrate that osteoclast function is fundamental in the HSC niche. View Publication

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产品号#：

03434

03444

05350

产品名：

MethoCult™GF M3434

MethoCult™GF M3434