Modeling Host-Microbe Interactions Using Human Intestinal Organoids
A common challenge to studying host-microbe interactions is the lack of optimal in vitro culture systems to recapitulate in vivo infection. In this virtual paper presentation, Dr. Devanjali Dutta discusses her research using human intestinal and lung organoids to study Cryptosporidium infection. Cryptosporidium is a protozoan parasite, a leading cause of diarrhea, and a major cause of child mortality worldwide. Dr. Dutta describes how she—and her colleagues in the lab of Dr. Hans Clevers—infected intestinal and lung organoids derived from healthy human donors with Cryptosporidium. In their paper*, organoids are presented as a physiologically relevant in vitro model to study Cryptosporidium and other pathogenic infections.
Dr. Devanjali Dutta is a Postdoctoral researcher in the lab of Dr. Hans Clever at the Hubrecht Institute.
*Heo I, Dutta D et al. (2018) Nat Microbiol. 3(7):814–23.
“Neuronal Diversity” Featuring Dr. Paola Arlotta
On this episode of the Stem Cell Podcast, Dr. Paola Arlotta from Harvard University talks about brain organoids as models for human development, neuropsychiatric disorders, and neurodegenerative diseases.
“Development of the Heart, Lung, and Vasculature” Featuring Dr. Mingxia Gu
On this episode of the Stem Cell Podcast, Dr. Mingxia Gu from Cincinnati Children’s Hospital discusses developing lung organoids to study COVID-19, how multi-lineage organoids can mimic human tissues, and her lab’s motto to “move fast and break things.”
Organoid Expert Panel
What could organoids do for your research? In this in-depth panel discussion, STEMCELL's organoid experts answer questions submitted by you. Topics include evaluating organoids as tissue and disease models, variability in organoid cultures, and future outlooks in translational and clinical applications.
Qi Tan, PhD
Dr. Qi Tan describes his work studying how epithelial cells maintain lung epithelial-mesenchymal homeostasis and protect the lung from fibrosis
EasySep™小鼠TIL（CD45）正选试剂盒
Modeling Host-Microbe Interactions Using Human Intestinal Organoids A common challenge to studying host-microbe interactions is the lack of optimal in vitro culture systems to recapitulate in vivo infection. In this virtual paper presentation, Dr. Devanjali Dutta discusses her research using human intestinal and lung organoids to study Cryptosporidium infection. Cryptosporidium is a protozoan parasite, a leading cause of diarrhea, and a major cause of child mortality worldwide. Dr. Dutta describes how she—and her colleagues in the lab of Dr. Hans Clevers—infected intestinal and lung organoids derived from healthy human donors with Cryptosporidium. In their paper*, organoids are presented as a physiologically relevant in vitro model to study Cryptosporidium and other pathogenic infections.
“Neuronal Diversity” Featuring Dr. Paola Arlotta On this episode of the Stem Cell Podcast, Dr. Paola Arlotta from Harvard University talks about brain organoids as models for human development, neuropsychiatric disorders, and neurodegenerative diseases.
“Development of the Heart, Lung, and Vasculature” Featuring Dr. Mingxia Gu On this episode of the Stem Cell Podcast, Dr. Mingxia Gu from Cincinnati Children’s Hospital discusses developing lung organoids to study COVID-19, how multi-lineage organoids can mimic human tissues, and her lab’s motto to “move fast and break things.”
Organoid Expert Panel What could organoids do for your research? In this in-depth panel discussion, STEMCELL's organoid experts answer questions submitted by you. Topics include evaluating organoids as tissue and disease models, variability in organoid cultures, and future outlooks in translational and clinical applications.
Qi Tan, PhD Dr. Qi Tan describes his work studying how epithelial cells maintain lung epithelial-mesenchymal homeostasis and protect the lung from fibrosis
Building Three-Dimensional Human Brain Organoids Overview of brain organogenesis and the applications of brain organoids in studying the development and maturation of the nervous system
