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Optimization of ALDEFLUOR™ Assay for Detection of ALDH Activity in Your Cell Type of Interest ALDEFLUOR™ reagent system is a non-immunological method to identify human stem and progenitor cells based on their aldehyde dehydrogenase (ALDH) activity

How to Identify ALDH-Expressing Cells in Human Breast Tissue

Mammary Stem Cells and Breast Cancer The mammary gland is composed of a series of branched epithelial ducts that drain alveolar structures during lactation, with the epithelium embedded within a fibrous and fatty stroma

Enhance Sensitivity of Multiple Myeloma Testing with Purified CD138+ Plasma Cells .

Assays for Mammary Epithelial Stem and Progenitor Cells .

Optimization of ALDEFLUOR™ Protocol Learn how STEMCELL Technologies' scientists doubled the signal strength in mammary epithelial cells with a few simple protocol modifications using ALDEFLUOR™ to detect Aldehyde Dehydrogenase bright (ALDHbr) cells

Frequently Asked Questions on CD138⁺ Cell Isolation for Increased FISH Sensitivity

Tumorsphere Culture of Human Breast Cancer Cell Lines .

Production of Chimeric Antigen Receptor T Cells This free Nature Protocols Wallchart summarizes the processes involved in producing CAR T cells for therapy.

How to Detect and Isolate Normal and Cancer Stem Cells Based on ALDH Activity with ALDEFLUOR™ An innovative, antibody-free system to rapidly identify stem and progenitor cells of several tissue types, including a variety of cancer stem cells

Non-Viral CRISPR Knock-In Anti-B7-H3 CAR-T Cells Are Amenable for Treatment of Subtypes of Small Cell Lung Cancer In this webinar, Scientist Vimal Keerthi discusses his work on identifying CD276 (B7-H3) overexpression in primary human SCLC and developing a non-viral CRISPR-Cas9 knock-in (CKI) based platform against B7-H3 to manufacture CAR T cells for the treatment of SCLC. He demonstrates the feasibility of this CAR T manufacturing platform and how this provides a blueprint for immediate clinical translation, overcoming the bottleneck of viral vector production.

This webinar is part of the “Translational T Cell Talks: Scaling for the Future” event hosted in collaboration with Scientist.com on June 11, 2024. View the rest of the talks and read the Q&A transcripts.

Natural Killer Cells Overview of NK cell receptors, subsets, activation and function