搜索结果: 'stemprep kits'

新闻
STEMCELL Technologies Introduces STEMprep™ Tissue Dissociator System to Accelerate Research Discoveries

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发布日期: 06/27/2025
技术手册
Generation of Human Pancreatic Organoids Using PancreaCult™ Organoid Medium Kits

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技术公告
Isolating Extracellular Vesicles from Urine with EasySep™ EV Human Positive Selection Kits

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细胞类型：

其他细胞系

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发布日期: 01/01/2024
技术手册
Generation of T Cells Using STEMdiff™ or StemSpan™ T Cell Kits

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09605

09915

09925

09930

09940

100-0194

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StemSpan™ SFEM II

StemSpan™淋系祖细胞扩增添加物（10X）

StemSpan™淋系祖细胞分化包板材料（100X）

StemSpan™ T细胞祖细胞成熟添加物（10X）

StemSpan™ T细胞生成试剂盒

STEMdiff™ T细胞试剂盒
技术窍门
Isolate Virtually Any Cell Type Using EasySep™ or EasySep™ Release Indirect Selection Kits

发布日期: 06/28/2013
20:24

线上讲座
STEMdiff™ Kits for Robust and Efficient Differentiation of hPSCs to Multiple Cell Types

发布日期: 06/24/2016
20:24

视频
STEMdiff™ Kits for Robust and Efficient Differentiation of hPSCs to Multiple Cell Types

发布日期: 06/24/2016
新闻
Applied Cells Enters into a Supply Agreement with STEMCELL Technologies on Reagent Kits for Use in a Next-Generation Solution for Cell Separation

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发布日期: 04/19/2022
技术公告
使用STEMprep™小鼠肿瘤解离试剂盒保留细胞表面表位完整性

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细胞类型：

肿瘤细胞

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发布日期: 06/26/2025
产品手册
简化您的组织处理流程-STEMprep™自动化组织处理器

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STEMprep

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Zhu HH et al. (MAY 2011) Blood 117 20 5350--61

Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool.

The stem cell factor (SCF)/Kit system has served as a classic model in deciphering molecular signaling events in the hematopoietic compartment,and Kit expression is a most critical marker for hematopoietic stem cells (HSCs) and progenitors. However,it remains to be elucidated how Kit expression is regulated in HSCs. Herein we report that a cytoplasmic tyrosine phosphatase Shp2,acting downstream of Kit and other RTKs,promotes Kit gene expression,constituting a Kit-Shp2-Kit signaling axis. Inducible ablation of PTPN11/Shp2 resulted in severe cytopenia in BM,spleen,and peripheral blood in mice. Shp2 removal suppressed the functional pool of HSCs/progenitors,and Shp2-deficient HSCs failed to reconstitute lethally irradiated recipients because of defects in homing,self-renewal,and survival. We show that Shp2 regulates coordinately multiple signals involving up-regulation of Kit expression via Gata2. Therefore,this study reveals a critical role of Shp2 in maintenance of a functional HSC/progenitor pool in adult mammals,at least in part through a kinase-phosphatase-kinase cascade. View Publication

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03434

03444

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MethoCult™ GF M3434

MethoCult™ GF M3434
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Instrument Service

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STEMprep

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21000

20119

20155

22001

22005

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22007

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22009

22011

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22013

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RoboSep™- S

RoboSep™ 吸头组件抛光剂

RoboSep™分选管套装（9个塑料管）

STEMvision™ 人脐带血7-天CFU分析包

STEMvision™ 彩色人脐带血14-天CFU分析包

STEMvision™ 彩色人骨髓14-天CFU分析包

STEMvision™ 彩色人动员外周血14-天CFU分析包

STEMvision™ 小鼠总CFU分析包

STEMvision™ 小鼠髓系CFU分析包

STEMvision™ 小鼠红系CFU分析包

STEMvision™ 小鼠CFU分析包（髓系和红系）