抗人CD25抗体，克隆BC96

抗人、恒河猴、食蟹猴CD25的小鼠单克隆IgG1抗体

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产品号 #60158_C

抗人、恒河猴、食蟹猴CD25的小鼠单克隆IgG1抗体

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总览

实验数据

产品说明书及文档

应用领域

总览

BC96抗体可特异性识别人CD25（一种55 kDa的I型跨膜糖蛋白）。CD25参与淋巴细胞的激活和扩增过程，可用于鉴定HIV和HTLV等病毒感染中的T细胞亚群。CD25存在于激活的T细胞和B细胞、单核细胞、巨噬细胞以及调节性T细胞中。CD25、CD4 和 FOXP3的表达被认为是调节性T细胞的表型特征。CD25对其IL-2配体的亲和力较低，但可与 IL-2 受体β（CD122）和常见的γ（CD132）链结合，形成高亲和力的IL-2受体。

亚型
一抗

靶抗原
CD25

别名
IL‑2 受体 α 链，IL-2Ra，IL2Ra，Tac，p55

活性物种
Baboon，Chimpanzee，Cynomolgus，人，Macaque，Rhesus

偶联
Alexa Fluor 488，APC，Biotin 或生物素，FITC，PE，未偶联的

宿主物种
小鼠

细胞类型
B 细胞，T 细胞，T 细胞，调节性细胞

应用
流式细胞术

研究领域
癌症，免疫，移植研究，细胞治疗开发

克隆
BC96

基因编号
3559

同种型
IgG1，kappa

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实验数据

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, followed by a rat anti-mouse IgG1 antibody, FITC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21 (Catalog #60070), followed by a rat anti-mouse IgG1 antibody, FITC (solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, FITC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, FITC (Catalog #60070FI; solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, PE (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, PE (Catalog #60070PE; solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, APC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, APC (Catalog #60070AZ; solid line histogram).

Flow cytometry analysis of PHA-L-activated human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD25 Antibody, Clone BC96, Alexa Fluor® 488 (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, Alexa Fluor® 488 (Catalog #60070AD; solid line histogram).