Anti-Human Lysozyme Antibody, Polyclonal

总览

该兔多克隆抗体可与人溶菌酶发生反应。溶菌酶是一种分泌性蛋白，在各种组织和体液中含量较高，例如肝脏、关节软骨、唾液和泪液。这种多克隆抗体可用于需要检测溶菌酶的应用，例如免疫组织化学实验 (IHC-P)。它已验证可用于免疫细胞化学 (ICC)实验。

溶菌酶具有溶菌功能，可水解各种细菌肽聚糖细胞壁上的 β-1,4 糖苷键。溶菌酶还在调节促炎免疫反应中发挥重要作用。特别是，溶菌酶催化的细菌降解会导致炎症小体激活，并通过胞浆受体（如 NOD1 和 NOD2）募集巨噬细胞。除了在促进促炎反应方面发挥重要作用外，溶菌酶还通过降低AGE 诱导的 IL-6 产生来限制炎症发生。

亚型
一抗

靶抗原
Lysozyme

别名
1,4-β-N-乙酰胞壁酸酶C，LYZF1，溶菌酶 (LZM)

活性物种
人

偶联
未偶联的

宿主物种
兔

细胞类型
肠道细胞

种属
人

应用
免疫细胞化学，免疫荧光，免疫组化

研究领域
类器官

克隆
Not applicable

基因编号
4069

同种型
Not applicable

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实验数据

Figure 1. Anti-Human Lysozyme Antibody, Polyclonal is Suitable for Staining Primary Differentiated Intestinal Organoid Sections

Primary differentiated intestinal organoid sections from B10 ALI colon lines were deparaffinized and rehydrated with water. The sections went through an antigen retrieval step, were blocked, and then labeled with Anti-Human Lysozyme Antibody, Polyclonal, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 488 (Catalog #100-1082). Nuclei were counter-stained with DAPI (blue). Inset shows cells labeled with a rabbit IgG isotype control antibody, followed by Goat Anti-Rabbit IgG (H+L) Antibody, Polyclonal, iFluor™ 488 (with DAPI staining).