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抗人TNF-α抗体，克隆MT15B15

抗人TNF-α的小鼠单克隆IgG1抗体
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产品号 #100-1461_C

抗人TNF-α的小鼠单克隆IgG1抗体

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总览
实验数据
产品说明书及文档
应用领域
相关产品

总览

该小鼠单克隆抗体（克隆号 MT15B15）可与人肿瘤坏死因子α (TNF-α)发生反应。TNF-α是一种促炎细胞因子，主要由巨噬细胞和T细胞在感染和炎症反应中产生。TNF-α最初作为~26 kDa的跨膜前体产生，随后被金属蛋白酶加工成~17 kDa的可溶性产物。两种形式的TNF-α都以三聚体形式存在，并通过与TNFR1（存在于几乎所有人细胞类型表面）或TNFR2（位于免疫细胞和内皮细胞）结合发挥其作用。TNF-α 信号传导最初被认为具有肿瘤坏死作用，可导致炎症反应，包括血管扩张和水肿形成、白细胞粘附于上皮细胞以及血液凝固。TNF-α 在防御细菌、病毒和寄生虫感染方面也发挥着关键作用。

靶抗原
TNF-alpha
 
别名
Cachectin；DIF；DIF-alpha；分化诱导因子；TNF；TNF-α；TNF-a；TNFa；TNFA；TNFSF2；TNLG1F；肿瘤坏死因子；肿瘤坏死因子-α
 
活性物种
人
 
偶联
Biotin 或 生物素，PF488P，PF647P
 
宿主物种
小鼠
 
细胞类型
巨噬细胞，T 细胞
 
种属
人
 
应用
流式细胞术
 
研究领域
免疫
 
克隆
MT15B15
 
基因编号
7124
 
同种型
IgG1
 

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实验数据

Flow Cytometry Analysis Of Unstimulated And Stimulated Human PBMCs Labeled With Anti-Human TNF-alpha Antibody, Clone MT15B15, PF647P

Figure 1. Data for Anti-Human TNF-alpha Antibody, Clone MT15B15, PF647P

(A) Flow cytometry analysis of unstimulated human peripheral blood mononuclear cells (PBMCs) labeled with anti-human TNF-alpha Antibody, Clone MT15B15, PF647P and anti-human CD8a antibody, clone RPA-T8, PE (Catalog #60022PE). (B) Flow cytometry analysis of PMA/ionomycin-stimulated human peripheral blood mononuclear cells (PBMCs) labeled with anti-human TNF-alpha Antibody, Clone MT15B15, PF647P and anti-human CD8a antibody, clone RPA-T8, PE (Catalog #60022PE).

Flow Cytometry Analysis Of Unstimulated And Stimulated Human PBMCs Labeled With Anti-Human TNF-alpha Antibody, Clone MT15B15, PF488P

Figure 2. Data for Anti-Human TNF-alpha Antibody, Clone MT15B15, PF488P

(A) Flow cytometry analysis of unstimulated human peripheral blood mononuclear cells (PBMCs) labeled with anti-human TNF-alpha Antibody, Clone MT15B15, PF488P and anti-human CD8a antibody, clone RPA-T8, APC (Catalog #60022AZ.1). (B) Flow cytometry analysis of PMA/ionomycin-stimulated human peripheral blood mononuclear cells (PBMCs) labeled with anti-human TNF-alpha Antibody, Clone MT15B15, PF488P and anti-human CD8a antibody, clone RPA-T8, APC (Catalog #60022AZ.1).

产品说明书及文档

请在《产品说明书》中查找相关支持信息和使用说明，或浏览下方更多实验方案。

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Anti-Human TNF-alpha Antibody, Clone MT15B15, PF488P
Catalog #
100-1462
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human TNF-alpha Antibody, Clone MT15B15, PF647P
Catalog #
100-1461
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human TNF-alpha Antibody, Clone MT15B15, Biotin
Catalog #
100-1463
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human TNF-alpha Antibody, Clone MT15B15, PF488P
Catalog #
100-1462
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human TNF-alpha Antibody, Clone MT15B15, PF647P
Catalog #
100-1461
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human TNF-alpha Antibody, Clone MT15B15, Biotin
Catalog #
100-1463
Lot #
All
Language
English

应用领域

本产品专为以下研究领域设计，适用于工作流程中的高亮阶段。探索这些工作流程，了解更多我们为各研究领域提供的其他配套产品。

Research Area
Workflow Stages

更多信息

更多信息
种属 Human
克隆 MT15B15
Gene Id 7124
Alternative Names Cachectin, DIF, DIF-alpha, differentiation inducing factor, TNF, TNF-α, TNF-a, TNFa, TNFA, TNFSF2, TNLG1F, tumor necrosis factor, tumor necrosis factor-α
同种型/isotype IgG1
质量保证:

产品仅供研究使用，不用于针对人或动物的诊断或治疗。
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