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Non-Viral CRISPR Knock-In Anti-B7-H3 CAR-T Cells Are Amenable for Treatment of Subtypes of Small Cell Lung Cancer In this webinar, Scientist Vimal Keerthi discusses his work on identifying CD276 (B7-H3) overexpression in primary human SCLC and developing a non-viral CRISPR-Cas9 knock-in (CKI) based platform against B7-H3 to manufacture CAR T cells for the treatment of SCLC. He demonstrates the feasibility of this CAR T manufacturing platform and how this provides a blueprint for immediate clinical translation, overcoming the bottleneck of viral vector production.

This webinar is part of the “Translational T Cell Talks: Scaling for the Future” event hosted in collaboration with Scientist.com on June 11, 2024. View the rest of the talks and read the Q&A transcripts.

Generation of Microglia From Human Pluripotent Stem Cells for Neurodegenerative Disease Modeling

High-Throughput Immunodensity-Based Cell Subset Isolation Directly from Whole Blood

Workflow Solutions for Human T Cell Isolation and Expansion .

Isolation of Human CD4+CD25+Bright/Foxp3+ Regulatory T Cells Directly from Whole Blood .

Reducing Platelet Contamination in Blood Samples Platelets (thrombocytes), cell fragments derived from megakaryocytes, are used in normal blood clotting, and must be handled gently to prevent activation

Fast and Easy Isolation of CD27-Positive Human Memory B Cells Using EasySep™ Releasable RapidSpheres™

The Human Leukocyte Antigen (HLA) Complex Provides an overview of the human leukocyte antigen (HLA) complex and nomenclature of HLA alleles

“Dendritic Cells and the Immune System” Featuring Dr. Caetano Reis e Sousa On this episode of the Immunology Podcast, Dr. Caetano Reis e Sousa talks about the mechanisms of dendritic cell cross-presentation, RNA interference, and dendritic cell progenitors in influenza.

Immunomagnetic Purification of Human Central and Effector Memory T Cell Subsets in 45 Minutes

Dissecting the Innate Immune Response in Human Intestinal Organoid Models

Removing Granulocytes from Old Blood Samples Technical tip from our dedicated team of Product and Scientific Support specialists