This Episode's Stem Cell Roundup:

• Study Reveals Immune Driver of Brain Aging – Researchers have identified a key factor in mental aging, and have suggested that it might be prevented or reversed by reprogramming myeloid glucose metabolism.
• A Tonsil Organoid System for Studying Adaptive Immunity – Scientists have developed a tonsil organoid system, and used it to evaluate immune responses to rabies and SARS-Cov-2 vaccines.
• Antisense Oligonucleotide Targets IRF4 Gene to Treat Multiple Myeloma – Researchers have shown that silencing IRF4 with an antisense oligonucleotide impairs myeloma cell survival and promotes sensitivity to clinical drugs.
• Illuminating the Path to Cervical Cancers – By creating novel organoid models, scientists have established a new approach to studying the biology of the cervix, and have identified key turning points in cancer development.