EasySep™小鼠TIL（CD45）正选试剂盒
产品号 #78104_C
双调蛋白
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总览
双调蛋白是表皮生长因子（EGF）家族的一员。它可结合多种受体，包括EGFR/ErbB1、HER2/ErbB2、HER3/ErbB3和HER4/ErbB4，从而激活Ras/Raf/MAPK和PI3K/AKT信号通路。引发细胞增殖、抗凋亡和侵袭行为（Normanno et al.）。双调蛋白的表达通常受组织损伤和炎症的诱导。可促进乳腺发育、滋养层细胞生长、肺和肾分支形态发生以及角质形成细胞增殖。它还可以刺激多种细胞类型的生长，包括正常和转化的乳腺上皮细胞，以及结肠、前列腺、宫颈和胰腺等恶性细胞（Berasain & Avila）。
亚型
细胞因子
别名
AR；AREG；AREGB；结直肠细胞衍生生长因子；CRDGF；MGC13647；神经鞘瘤衍生生长因子；SDGF
细胞类型
气道细胞，乳腺细胞
种属
人
研究领域
上皮细胞研究
分子量
11.3 千道尔顿
纯度
≥ 95 %
实验数据
(A) The biological activity of Human Recombinant Amphiregulin was tested by its ability to promote the proliferation of BALB/c 3T3 cells. Cell proliferation was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is less than 0.2 ng/mL. (B) 2 μg of Human Recombinant Amphiregulin was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining.
产品说明书及文档
请在《产品说明书》中查找相关支持信息和使用说明，或浏览下方更多实验方案。
Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human Recombinant Amphiregulin Catalog #
78104.1 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human Recombinant Amphiregulin Catalog #
78104.1 Lot #
All Language
English 应用领域
本产品专为以下研究领域设计，适用于工作流程中的高亮阶段。探索这些工作流程，了解更多我们为各研究领域提供的其他配套产品。
Research Area
Workflow Stages
Workflow Stages for Airway Epithelial Cell Research
相关材料与文献
技术资料 (2)
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更多信息
| Molecular Weight | 11.3 kDa |
|---|---|
| 种属 | Human |
| Alternative Names | AR, AREG, AREGB, Colorectum cell-derived growth factor, CRDGF, MGC13647, Schwannoma-derived growth factor, SDGF |
| 纯度 | ≥ 95% |
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产品仅供研究使用，不用于针对人或动物的诊断或治疗。
产品仅供研究使用，不用于针对人或动物的诊断或治疗。
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