产品号 #100-0937_C
脂联素球状结构域,30 kDa脂肪细胞成分相关蛋白,无动物源成分
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脂联素也被称为脂肪细胞成分相关蛋白,分子量为30kda,是防御胶原蛋白家族的成员,其结构与补体相关蛋白家族成员c1q相似(Chandran等)。脂联素由分化的脂肪细胞表达,它由三个确定的结构域组成:含N端高变区,含22个GXY重复序列的胶原样柄区,接着是c端球状结构域(Wang等)。研究表明,脂联素也被确定为一种造血干细胞生长因子(DiMascio等人),并且在调节骨髓间充质干细胞微环境中发挥作用(Yu等人)。脂联素的球形结构域(gAcrp30)可以显著降低小鼠体内游离脂肪酸和葡萄糖水平(Wong等),并调控心肌细胞中葡萄糖和脂肪酸的摄取和氧化(Palanivel等)。本产品不含动物源成分。
别名
Acrp30;AdipoQ;APM-1;GBP-28;脂联素的球状结构域
细胞类型
造血干/祖细胞,间充质干/祖细胞
种属
人
研究领域
干细胞生物学
制剂类别
Animal Component-Free
纯度
≥ 90%
Figure 1.
(A) The biological activity of Human Recombinant gAdiponectin (gAcrp30), ACF was tested by its ability to inhibit M1 cell proliferation. The EC50 is defined as the effective concentration of growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is 521 ng/mL. (B) Human Recombinant gAdiponectin (gAcrp30), ACF was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant gAdiponectin (gAcrp30), ACF has a predicted molecular mass of 16.7 kDa.
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种属 | Human |
---|---|
配方类别 | Animal Component-Free |
Alternative Names | Acrp30, AdipoQ, APM-1, GBP-28, globular domain of adiponectin |
纯度 | ≥ 90% |
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