EasySep™小鼠TIL（CD45）正选试剂盒
产品号 #78110_C
生长分化因子11
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总览
生长分化因子11 （GDF-11）是转化生长因子β (TGF-β)家族一员。它通过结合TGF-β受体ALK4、ALK5和ALK7，激活SMAD信号通路（Ho et al.）。GDF-11可调节嗅觉系统、视网膜和胰腺的发育，以及身体轴骨骼的前后极性模式建立（Lee & Lee）。GDF-11是一种内分泌因子，在骨骼肌、脑组织和牙髓中表达的（Kondás et al.）。小鼠研究表明，GDF-11能调节肌肉和心脏的衰老过程，并通过重塑血管刺激神经发生(Katsimpardi et al.; Loffredo et al.; Sinha et al.)。
亚型
细胞因子
细胞类型
神经细胞，PSC衍生
种属
人，小鼠
研究领域
神经科学，干细胞生物学
纯度
≥ 95 %
实验数据
(A) The biological activity of Human/Mouse Recombinant GDF-11 was tested by its ability to inhibit alkaline phosphatase production in ATDC-5 cells. Inhibition of alkaline phosphatase production was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which alkaline phosphatase activity is at 50% of maximum. The EC50 in the above example is 2.63 ng/mL. (B) 1 μg of Human/Mouse Recombinant GDF-11 was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining.
产品说明书及文档
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Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet Product Name
Human/Mouse Recombinant GDF-11 Catalog #
78110.1, 78110 Lot #
All Language
English Document Type
Safety Data Sheet Product Name
Human/Mouse Recombinant GDF-11 Catalog #
78110.1, 78110 Lot #
All Language
English 应用领域
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Research Area
Workflow Stages
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更多信息
| 种属 | Human, Mouse |
|---|---|
| 纯度 | ≥ 95% |
质量保证:
产品仅供研究使用，不用于针对人或动物的诊断或治疗。
产品仅供研究使用，不用于针对人或动物的诊断或治疗。
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