产品号 #78043_C
白介素33
若您需要咨询产品或有任何技术问题,请通过官方电话 400 885 9050 或邮箱 info.cn@stemcell.com 与我们联系
白介素33 (IL-33)是IL-1家族的促炎细胞因子。它与ST2受体结合,激活NF-κB和MAPK通路。IL-33在各种组织和器官中的上皮细胞、平滑肌细胞和成纤维细胞,以及静止的嗜碱性细胞、肥大细胞、嗜酸性细胞、天然辅助细胞、2组先天淋巴样细胞、树突状细胞和活化的巨噬细胞中表达(Schmitz et al.; Yasuda et al.)。它通过刺激细胞因子IL-4、IL-5和IL-13的产生,促进过敏性炎症,并刺激宿主防御微生物和病毒感染(Liew; Yasuda et al.)。在中枢神经系统中,IL-33由内皮细胞和星形胶质细胞产生。它诱导小胶质细胞增殖并介导促炎细胞因子的产生(Yasuoka et al.)。
亚型
细胞因子
细胞类型
单核细胞,T 细胞,其他亚群
种属
人
研究领域
免疫
纯度
≥ 95 %
(A) The biological activity of Human Recombinant IL-33 was tested by its ability to promote the proliferation of D10S cells in low serum medium containing no other cytokines. Cell proliferation was measured after 67 hours of culture using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the above example is 0.1 - 0.15 ng/mL.
(B) 1 μg of Human Recombinant IL-33 was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant IL-33 has a predicted molecular mass of 18.1 kDa.
请在《产品说明书》中查找相关支持信息和使用说明,或浏览下方更多实验方案。
Thank you for your interest in IntestiCult™ Organoid Growth Medium (Human). Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):
Estimated delivery time for your area
Product sample or exclusive offer
In-lab demonstration
扫描二维码或搜索微信号STEMCELLTech,即可关注我们的微信平台,第一时间接收丰富的技术资源和最新的活动信息。
如您有任何问题,欢迎发消息给STEMCELLTech微信公众平台,或与我们通过电话/邮件联系:400 885 9050 INFO.CN@STEMCELL.COM。