In this webinar, Dr. Satiro De Oliveira, University of California, Los Angeles discusses how humanized mouse models facilitate in vivo studies of hematopoiesis. He gives an overview of the generation of humanized mice through engraftment of hematopoietic stem cells into the bone marrow of NOD scid gamma (NSG) mice, as well as the benefits and potential pitfalls of humanized mouse models in cancer immunotherapy and gene therapy.