Genetic instability in human pluripotent stem cells (hPSCs) can be exacerbated by prolonged in vitro culture or cellular stress, including the use of routine single-cell passaging. However, single-cell passaging may be required for obtaining higher-density cultures, or compatibility with single cell workflows.

In this Innovation Showcase talk from ISSCR 2023, one of STEMCELL’s Senior Scientists, Dr. Adam Hirst, introduces eTeSR™, a novel hPSC maintenance medium developed specifically to maintain cell quality when passaging hPSCs as single cells. The formulation is optimized to support hPSC expansion while reducing cellular stress. When tested against other commercially available media, hPSCs routinely maintained as single cells in eTeSR™ demonstrate higher genetic stability.

As a sponsor of, and participant in, ISSCR’s 2023 Annual Meeting, we share with you our Innovation Showcase presentation at #ISSCR2023. This presentation does not represent an endorsement from or support of the ISSCR.