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“Manipulating Stem Cell Fate” Featuring Dr. Shuibing Chen
“Manipulating Stem Cell Fate” Featuring Dr. Shuibing Chen
Dr. Shuibing Chen is the Kilts Family Professor of Surgery at Weill Cornell Medicine. Her lab uses hiPSCs and ESCs for disease modeling and drug screening, with a focus on diabetes and infectious diseases such as Zika and SARS-CoV-2. She talks about her recent genome-wide association study in a dish, the role of philanthropic funding in stem cell research, and the role of industry partnerships in translational research.
Dr. Shuibing Chen is a stem cell biologist trained as an expert in pancreatic development, but she does a little bit of everything these days when it comes to disease modeling and drug screening. Her lab has been extremely productive in the last few years, using organoid models to study a variety of diseases ranging from cardiovascular disease to diabetes and even modeling COVID-19 in a dish!
Dr. Arun Sharma, host
Find more episodes at stemcellpodcast.com or wherever you get your podcasts.
This Episode's Stem Cell Roundup:
- Rethinking Hippo Signaling – Scientists found that Hippo signaling is not needed for normal organ growth.
- Muscle Stem Cell Regeneration – Researchers identified a subset of dysfunctional aged muscle stem cells with elevated levels of CD47.
- Inner Ear Organoids – Scientists used organoids to investigate how CHD7 mutations affect inner ear development.
- Islet Transplants Without Immunosuppression – Simultaneous hematopoietic cell and islet transplantation corrects diabetes in mice.
