Predictive In Vitro Models for Toxicity Testing and Liver Research

Having validated tools to perform predictive assays in a biologically-relevant system is key to success in drug discovery research. In this webinar, Dr. Terry Riss (Promega Corp) and Jennifer Christie (STEMCELL Technologies) discuss products and protocols that enable the incorporation of validated in vitro alternatives to animal models for toxicology studies. First, Dr. Riss presents in vitro assays for 3D cultures that monitor drug-induced cytotoxicity and explains how different assays can be multiplexed to measure multiple cell health parameters. Following this, Ms. Christie describes how to generate mature and functional hepatic organoids using HepatiCult™ and demonstrates their applications in liver research and hepatotoxicity assessment.