技术资料

技术公告
使用StemSpan™白血病细胞培养试剂盒进行体外药物筛选

细胞类型：

癌细胞及细胞系，白血病/淋巴瘤细胞，造血干祖细胞

发布日期: 05/01/2023
3:39

视频
How to Count hPSC Aggregates to Determine Plating Density for Maintenance and Differentiation

发布日期: 10/14/2019
2:13

视频
STEMCELL Technologies Inc. Training Programs

发布日期: 07/02/2019
技术公告
Expansion and Differentiation of Hematopoietic Stem and Progenitor Cells into Natural Killer (NK) Cells Using StemSpan™ Medium and Supplements

细胞类型：

NK细胞，造血干祖细胞

发布日期: 05/01/2024
7:30

视频
How to Standardize and Automate Hematopoietic Colony Counting in CFU Assays with STEMvision™

发布日期: 01/02/2019
技术公告
Evaluation of Genome Editing

细胞类型：

T细胞，多能干细胞，造血干祖细胞

发布日期: 02/01/2022
挂图
Mouse Hematopoietic Stem and Progenitor Cell Phenotyping Overview of mouse HSPC subset surface markers and frequencies

发布日期: 08/10/2018
Wu X et al. (JAN 2018) Cell 172 3 423--438.e25

Intrinsic Immunity Shapes Viral Resistance of Stem Cells.

Stem cells are highly resistant to viral infection compared to their differentiated progeny; however,the mechanism is mysterious. Here,we analyzed gene expression in mammalian stem cells and cells at various stages of differentiation. We find that,conserved across species,stem cells express a subset of genes previously classified as interferon (IFN) stimulated genes (ISGs) but that expression is intrinsic,as stem cells are refractory to interferon. This intrinsic ISG expression varies in a cell-type-specific manner,and many ISGs decrease upon differentiation,at which time cells become IFN responsive,allowing induction of a broad spectrum of ISGs by IFN signaling. Importantly,we show that intrinsically expressed ISGs protect stem cells against viral infection. We demonstrate the in vivo importance of intrinsic ISG expression for protecting stem cells and their differentiation potential during viral infection. These findings have intriguing implications for understanding stem cell biology and the evolution of pathogen resistance. View Publication

产品号#：

02691

04434

04444

05110

05711

05712

05872

05873

18056

18056RF

72052

72054

72302

72304

72307

72308

70039

70039.1

70039.2

70039.3

70039.4

70039.5

70039.6

60062

60062BT

60062FI

60062FI.1

60062PE

60062PE.1

60045

60045AZ

60045AZ.1

60045BT

60045FI

60045FI.1

600

产品名：

StemSpan™CD34+扩增补充（10X）

MethoCult™H4434经典

MethoCult™H4434经典

STEMdiff™定型内胚层检测试剂盒

NeuroCult™ SM1 神经添加物

CHIR99021

CHIR99021

Y-27632（二盐酸盐）

Y-27632（二盐酸盐）

Y-27632（二盐酸盐）

Y-27632（二盐酸盐）

Anti-Human SSEA-4 Antibody, Clone MC-813-70，Biotin

Anti-Human SSEA-4 Antibody, Clone MC-813-70，FITC

抗人SSEA-4抗体, Clone MC-813-70，FITC

Anti-Human SSEA-4 Antibody, Clone MC-813-70，PE

Anti-Human SSEA-4 Antibody, Clone MC-813-70，PE

抗人CD90抗体, 克隆号5E10

抗人CD90抗体，克隆5E10，APC

抗人CD90抗体，克隆5E10，APC

抗人CD90抗体，克隆5E10，Biotin

抗人CD90抗体，克隆5E10，FITC

抗人CD90抗体，克隆5E10，FITC
Scalzo-Inguanti K et al. (MAY 2017) Journal of leukocyte biology

A neutralizing anti-G-CSFR antibody blocks G-CSF-induced neutrophilia without inducing neutropenia in nonhuman primates.

Neutrophils are the most abundant WBCs and have an essential role in the clearance of pathogens. Tight regulation of neutrophil numbers and their recruitment to sites of inflammation is critical in maintaining a balanced immune response. In various inflammatory conditions,such as rheumatoid arthritis,vasculitis,cystic fibrosis,and inflammatory bowel disease,increased serum G-CSF correlates with neutrophilia and enhanced neutrophil infiltration into inflamed tissues. We describe a fully human therapeutic anti-G-CSFR antibody (CSL324) that is safe and well tolerated when administered via i.v. infusion to cynomolgus macaques. CSL324 was effective in controlling G-CSF-mediated neutrophilia when administered either before or after G-CSF. A single ascending-dose study showed CSL324 did not alter steady-state neutrophil numbers,even at doses sufficient to completely prevent G-CSF-mediated neutrophilia. Weekly infusions of CSL324 (%10 mg/kg) for 3 wk completely neutralized G-CSF-mediated pSTAT3 phosphorylation without neutropenia. Moreover,repeat dosing up to 100 mg/kg for 12 wk did not result in neutropenia at any point,including the 12-wk follow-up after the last infusion. In addition,CSL324 had no observable effect on basic neutrophil functions,such as phagocytosis and oxidative burst. These data suggest that targeting G-CSFR may provide a safe and effective means of controlling G-CSF-mediated neutrophilia as observed in various inflammatory diseases. View Publication

产品号#：

70008

70008.1

70008.2

70008.3

70008.4

70008.5

70008.6

200-0000

200-0001

200-0002

70002

70002.1

70002.2

70002.3

70002.4

70002.5

产品名：

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞

冻存的人脐带血CD34+细胞
科学海报
Generation of T Cells from Hematopoietic Stem and Progenitor Cells in a Stroma-Free, Serum-Free Culture System
2:22

视频
How ALDEFLUOR™ ALDH Assay Kit Detects Normal and Cancer Progenitor Cells

发布日期: 12/04/2017
5:43

视频
How to Set Up Hematopoietic Colony-Forming Unit (CFU) Assays

发布日期: 10/06/2017