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抗小鼠EPCR抗体，克隆RMEPCR1560（1560）

抗小鼠EPCR（CD201）大鼠单克隆IgG2b抗体
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产品号 #（选择产品）

产品号 #60038_C

抗小鼠EPCR（CD201）大鼠单克隆IgG2b抗体

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总览
实验数据
产品说明书及文档
应用领域
相关材料与文献
相关产品

总览

RMEPCR1560 (1560) 抗体可与内皮细胞蛋白C受体（EPCR或CD201）发生反应。EPCR是一种分子量约为25 kDa的I型跨膜糖蛋白，由内皮细胞、部分造血干细胞（HSC）亚群、树突状细胞以及多种恶性细胞系表达。它也以可溶形式存在于血浆中。EPCR与MHC 1类/CD1蛋白家族具有同源性。EPCR可与蛋白C和活化的蛋白C结合，从而增强凝血酶-血栓调节蛋白复合物对蛋白C的活化，并调节血液凝固和炎症。在约1.5%的小鼠骨髓细胞中检测到EPCR蛋白表达。纯化的EPCR+细胞具有高度富集的HSC活性，证明了高的体内再生活性。此外，EPCR 表达与使用常规标记分离的骨髓细胞群的干细胞活性相关，表明 EPCR 作为识别小鼠 HSC 的单一标记的有效性。

亚型
一抗
 
靶抗原
EPCR (CD201)
 
别名
活化蛋白C受体，APC受体，CCD41，CD201，内皮细胞蛋白C受体，PROCR，蛋白C受体
 
活性物种
小鼠
 
偶联
Biotin 或 生物素，FITC，PE，未偶联的
 
宿主物种
大鼠
 
细胞类型
内皮细胞，造血干/祖细胞
 
种属
小鼠
 
应用
细胞分选，流式细胞术，功能学筛选，免疫组化，Western印迹
 
研究领域
内皮细胞研究，干细胞生物学
 
克隆
RMEPCR1560 (1560)
 
基因编号
19124
 
同种型
IgG2b，kappa
 

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实验数据

Data for Unconjugated

Figure 1. Data for Unconjugated

Flow cytometry analysis of HEK-293 mEPCR-transfected cells (filled histogram) or non-transfected HEK-293 cells (negative control; dashed line histogram), labeled with Anti-Mouse EPCR Antibody, Clone RMEPCR1560, followed by Goat Anti-Mouse IgG (H+L) Antibody, Polyclonal, FITC (Catalog #60138FI). Labeling of HEK-293 mEPCR-transfected cells with a rat IgG2b, kappa isotype control antibody, followed by Goat Anti-Mouse IgG (H+L) Antibody, Polyclonal, FITC is shown (solid line histogram).

Data for Biotin-Conjugated

Figure 2. Data for Biotin-Conjugated

Flow cytometry analysis of HEK-293 mEPCR-transfected cells (filled histogram) or non-transfected HEK-293 cells (negative control cells, dashed line histogram), labeled with Anti-Mouse EPCR Antibody, Clone RMEPCR1560, Biotin followed by streptavidin (SAV) APC. Labeling of HEK-293 mEPCR-transfected cells with a rat IgG2b, kappa isotype control antibody followed by SAV APC is shown (solid line histogram).

Data for FITC-Conjugated

Figure 3. Data for FITC-Conjugated

Flow cytometry analysis of HEK-293 mEPCR-transfected cells (filled histogram) or non-transfected HEK-293 cells (negative control cells, dashed line histogram), labeled with Anti-Mouse EPCR Antibody, Clone RMEPCR1560 FITC. Labeling of HEK-293 mEPCR-transfected cells with a rat IgG2b, kappa FITC isotype control antibody is shown (solid line histogram).

Data for PE-Conjugated

Figure 4. Data for PE-Conjugated

Flow cytometry analysis of HEK-293 mEPCR-transfected cells (filled histogram) or non-transfected HEK-293 cells (negative control cells, dashed line histogram), labeled with Anti-Mouse EPCR Antibody, Clone RMEPCR1560, PE. Labeling of HEK-293 mEPCR-transfected cells with a rat IgG2b, kappa PE isotype control antibody is shown (solid line histogram).

产品说明书及文档

请在《产品说明书》中查找相关支持信息和使用说明，或浏览下方更多实验方案。

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560), FITC
Catalog #
100-1576
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560), FITC
Catalog #
60038FI.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560)
Catalog #
60038
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560), PE
Catalog #
60038PE
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560), Biotin
Catalog #
60038BT
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560), FITC
Catalog #
100-1576, 60038FI.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560)
Catalog #
60038
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560), PE
Catalog #
60038PE
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560), Biotin
Catalog #
60038BT
Lot #
All
Language
English

应用领域

本产品专为以下研究领域设计，适用于工作流程中的高亮阶段。探索这些工作流程，了解更多我们为各研究领域提供的其他配套产品。

Research Area
Workflow Stages

更多信息

更多信息
种属 Mouse
克隆 RMEPCR1560 (1560)
Gene Id 19124
Alternative Names Activated protein C receptor, APC receptor, CCD41, CD201, endothelial protein C receptor, PROCR, protein C receptor
同种型/isotype IgG2b, kappa
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