Scientific Resources

Highly Characterized Human iPSCs and NPCs for Downstream Differentiation Applications Reproducible research with human induced pluripotent stem cells (iPSCs) depends on access to thoroughly characterized and quality-controlled cell lines. In this webinar, Drs. Andrew Gaffney and Erin Knock will describe the generation of a standardized induced pluripotent stem cell (iPSC) line. Developed with the upcoming ISSCR Standards Initiative characterization guidelines in mind, this highly characterized line is karyotypically stable, demonstrates trilineage differentiation potential, and expresses undifferentiated cell markers. Further, STEMCELL has developed a highly pure, ready-to-use neural progenitor cell product expressing PAX6 and SOX1 over multiple passages. Dr. Knock will show how these multipotent cells are suitable for customized downstream differentiation to various CNS cell types, such as forebrain neurons, midbrain neurons, and astrocytes. These progenitor cells are the ideal controls for standardizing downstream differentiation protocols, modeling diseases, and developing assays.

Modeling Genetic Epilepsies with Induced Pluripotent Stem Cells

How to Harvest Reprogrammed iPS Cell Colonies in TeSR™-E7™ Reprogramming Culture Medium Characteristics of reprogrammed iPS cell colonies and provides instructions for manually harvesting putative iPS cell colonies for replating and further expansion

Whole Exome Sequencing Reveals Selective Pressures and Dominant Negative Mutations in hPSC Cultures

Large-Scale Expansion of Human Pluripotent Stem Cells in 3D Suspension Culture with mTeSR™3D Medium Features and benefits of mTeSR™3D, a specialized medium for expansion of human pluripotent stem cells in suspension culture, including the novel fed-batch culture system

Development and Validation of a Rapid ALDHbr-Based Cord Blood Potency Assay

Production of Chimeric Antigen Receptor T Cells This free Nature Protocols Wallchart summarizes the processes involved in producing CAR T cells for therapy.

Bone Marrow Niches and HSC Fates A detailed reference on signaling pathways in the bone marrow and how these influence HSC fate decisions; created in partnership with Nature Reviews Immunology and Nature Reviews Molecular Cell Biology

Targeting Self-Renewal Function in Normal Hematopoietic and Leukemic Stem Cells

How SepMate™ PBMC Isolation Tubes Work: From Whole Blood to PBMCs in 15 Minutes SepMate™, an innovative tube that enables consistent and hassle-free peripheral blood mononuclear cell (PBMC) isolation, for fast and easy PBMC isolation from whole blood in just 15 minutes using density gradient centrifugation

Human Hematopoietic Stem and Progenitor Cell Phenotyping Overview of subset surface markers, frequencies and assays for analysis

MesenCult™ for Mesenchymal Stromal Cell Derivation, Culture & Differentiation Use MesenCult™ to derive, culture, expand, differentiate, and cryopreserve MSCs