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抗小鼠TCR Gamma/Delta 抗体，克隆GL3

亚美尼亚仓鼠单克隆IgG2抗体，抗小鼠T细胞受体 gamma/delta
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产品号 #60104_C

亚美尼亚仓鼠单克隆IgG2抗体，抗小鼠T细胞受体 gamma/delta

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总览
实验数据
产品说明书及文档
应用领域
相关材料与文献
相关产品

总览

GL3抗体识别小鼠T细胞受体γ/δ （TCRγ/δ或TCR gamma/delta）的δ链，δ链是 TCR 的一种亚型，参与肽和脂质抗原的识别。TCRγ/δ是由二硫键连接的γ和δ亚基组成的异二聚体（在人体内约为 80 kDa），与细胞表面的 CD3 结合。它是免疫球蛋白超家族的成员。TCRγ/δ在循环中的T细胞亚群中表达，但在富含上皮细胞的组织中，多达50%的T细胞上都可发现TCRγ/δ。这些细胞在口腔和肿瘤相关耐受以及自身免疫性疾病中发挥作用，并被描述为适应性和先天免疫反应之间的纽带。一旦被激活，它们以亚型和环境特异性的方式分泌效应细胞因子。大多数γ/δ T 细胞是 CD4-/CD8-，但也有一些表达 CD8。GL3 抗体可识别δ链恒定区的表位，据报道可激活 TCRγ/δ+ 细胞。

亚型
一抗
 
靶抗原
T Cell Receptor Gamma/Delta
 
别名
γ/δ TCR，gdTCR，TCRgd，TCR γ/δ，T细胞受体δ链，T细胞受体γ链，T细胞受体γ/δ，T3D，T3G
 
活性物种
小鼠
 
偶联
Alexa Fluor 488，APC，Biotin 或 生物素，FITC，PE，未偶联的
 
宿主物种
Hamster
 
细胞类型
T 细胞，T 细胞，其他亚群
 
种属
小鼠
 
应用
细胞分选，删除，流式细胞术，功能学筛选，免疫荧光，免疫组化，免疫沉淀，中和及阻断
 
研究领域
免疫
 
克隆
GL3
 
基因编号
110066/110067
 
同种型
IgG2，kappa
 

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实验数据

Data for Unconjugated

Figure 1. Data for Unconjugated

(A) Flow cytometry analysis of C57BL/6 mouse lymph node cells labeled with Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, followed by an anti-hamster (Armenian) IgG antibody, FITC and Anti-Mouse CD3e Antibody, Clone 145-2C11, APC (Catalog #60015AZ).

Data for Alexa Fluor® 488-Conjugated

Figure 2. Data for Alexa Fluor® 488-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse lymph node cells labeled with Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, Alexa Fluor® 488 and Anti-Mouse CD3e Antibody, Clone 145-2C11, APC (Catalog #60015AZ).

Data for APC-Conjugated

Figure 3. Data for APC-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse lymph node cells labeled with Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, APC and Anti-Mouse CD3e Antibody, Clone 145-2C11, PE (Catalog #60015PE).

Data for Biotin-Conjugated

Figure 4. Data for Biotin-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse lymph node cells labeled with Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, Biotin followed by streptavidin (SAV) APC and Anti-Mouse CD3e Antibody, Clone 145-2C11, PE (Catalog #60015PE).

Data for FITC-Conjugated

Figure 5. Data for FITC-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse lymph node cells labeled with Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, FITC and Anti-Mouse CD3e Antibody, Clone 145-2C11, APC (Catalog #60015AZ).

Data for PE-Conjugated

Figure 6. Data for PE-Conjugated

(A) Flow cytometry analysis of C57BL/6 mouse lymph node cells labeled with Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, PE and Anti-Mouse CD3e Antibody, Clone 145-2C11, APC (Catalog #60015AZ).

产品说明书及文档

请在《产品说明书》中查找相关支持信息和使用说明，或浏览下方更多实验方案。

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, Alexa Fluor® 488
Catalog #
60104AD.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, APC
Catalog #
60104AZ, 60104AZ.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, Biotin
Catalog #
60104BT.1, 60104BT
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, FITC
Catalog #
60104FI.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, PE
Catalog #
60104PE, 60104PE.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3
Catalog #
60104
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, Alexa Fluor® 488
Catalog #
60104AD.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, APC
Catalog #
60104AZ, 60104AZ.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, Biotin
Catalog #
60104BT.1, 60104BT
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, FITC
Catalog #
60104FI.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3, PE
Catalog #
60104PE, 60104PE.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3
Catalog #
60104
Lot #
All
Language
English

应用领域

本产品专为以下研究领域设计，适用于工作流程中的高亮阶段。探索这些工作流程，了解更多我们为各研究领域提供的其他配套产品。

Research Area
Workflow Stages

相关材料与文献

技术资料 (2)

Reliable Antibodies for Your Research
Brochure
Reliable Antibodies for Your Research
Human Immune Cytokines
Wallchart
Human Immune Cytokines

更多信息

更多信息
种属 Mouse
克隆 GL3
Gene Id 110066/110067
Alternative Names Gamma/Delta TCR, gdTCR, TCRgd, TCR γ/δ, T cell receptor delta chain, T cell receptor gamma chain, T cell receptor γ/δ, T3D, T3G
同种型/isotype IgG2, kappa
法律声明:

Alexa Fluor is a registered trademark of Life Technologies Corporation. Antibodies conjugated to Alexa Fluor® are licensed for internal research use only and sale is expressly conditioned on the buyer not using the antibody for manufacturing, performing a service or medical test, or otherwise generating revenue. For use other than research, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.

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产品仅供研究使用，不用于针对人或动物的诊断或治疗。 欲获悉更多关于STEMCELL的质控信息，请访问 STEMCELL.CN/COMPLIANCE.
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