Studying Cystic Fibrosis Using Primary Human Nasal Epithelial Cells
Cystic Fibrosis (CF) is a genetic disease that affects multiple organs in the body. The primary defects are in the airway and related to epithelial dysfunction. Technological advances have enabled researchers to study CF using specialized in vitro cell culture models to recapitulate the pseudostratified airway epithelium. In this webinar, Dr. Theo Moraes elaborates on the advantages of using nasal epithelial cell cultures to perform such studies and their implications for precision medicine in CF. He also discusses the Program for Individualized Cystic Fibrosis Therapy (CFIT)—a collaboration between CF Canada, SickKids Foundation, and The Hospital for Sick Children—and how it utilizes the nasal culture methodology to develop a nationally accessible resource and to accelerate the development of individualized therapies for CF patients.
Dr. Theo Moraes is a clinician and researcher at The Hospital for Sick Children and the SickKids Research Institute in Toronto, Canada.
Jason Spence
Dr. Jason Spence describes his work on developing organoid systems to investigate tissue development and the physiology of immature tissues
Qi Tan, PhD
Dr. Qi Tan describes his work studying how epithelial cells maintain lung epithelial-mesenchymal homeostasis and protect the lung from fibrosis
“Development of the Heart, Lung, and Vasculature” Featuring Dr. Mingxia Gu
On this episode of the Stem Cell Podcast, Dr. Mingxia Gu from Cincinnati Children’s Hospital discusses developing lung organoids to study COVID-19, how multi-lineage organoids can mimic human tissues, and her lab’s motto to “move fast and break things.”
EasySep™小鼠TIL（CD45）正选试剂盒
How to Grow Cerebral Organoids from Human Pluripotent Stem Cells Guide for growing cerebral organoids, or brain organoids, from human pluripotent stem cells (hPSCs)
Studying Cystic Fibrosis Using Primary Human Nasal Epithelial Cells Cystic Fibrosis (CF) is a genetic disease that affects multiple organs in the body. The primary defects are in the airway and related to epithelial dysfunction. Technological advances have enabled researchers to study CF using specialized in vitro cell culture models to recapitulate the pseudostratified airway epithelium. In this webinar, Dr. Theo Moraes elaborates on the advantages of using nasal epithelial cell cultures to perform such studies and their implications for precision medicine in CF. He also discusses the Program for Individualized Cystic Fibrosis Therapy (CFIT)—a collaboration between CF Canada, SickKids Foundation, and The Hospital for Sick Children—and how it utilizes the nasal culture methodology to develop a nationally accessible resource and to accelerate the development of individualized therapies for CF patients.
Jason Spence Dr. Jason Spence describes his work on developing organoid systems to investigate tissue development and the physiology of immature tissues
Qi Tan, PhD Dr. Qi Tan describes his work studying how epithelial cells maintain lung epithelial-mesenchymal homeostasis and protect the lung from fibrosis
“Development of the Heart, Lung, and Vasculature” Featuring Dr. Mingxia Gu On this episode of the Stem Cell Podcast, Dr. Mingxia Gu from Cincinnati Children’s Hospital discusses developing lung organoids to study COVID-19, how multi-lineage organoids can mimic human tissues, and her lab’s motto to “move fast and break things.”
