Nature Research Round Table: Identifying Acquired and Background Genetic Variants in Human Pluripotent Stem Cells
Dr. Florian Merkle from the University of Cambridge talks about the implications of quality control during gene editing, in particular genetic variants that arise during routine culture and genetic variants that might have been acquired during the process of gene editing. This presentation and the following Q&A session were moderated by Dr. Alex Alderton from the Wellcome Trust Sanger Institute.
This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here.
Nature Research Round Table: Regulations Around Human Induced Pluripotent Stem Cell Registration
Dr. Andreas Kurtz from the Berlin-Brandenburg Center for Regenerative Therapies discusses data associated with human pluripotent stem cells (hPSCs) as well as the benefits of and regulations around data registration for cell line characterization. Since 2010, Dr. Kurtz has managed hPSCreg, a freely accessible global registry for human hPSC lines. This presentation and the following Q&A session were moderated by Dr. Joanne Mountford from the University of Glasgow.
This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here.
Next-Generation Tools for NK Cell Research
Natural killer (NK) cells are gaining popularity as a therapeutic tool for their unique ability to target and kill virus-infected and cancer cells without prior immune sensitization. Adopting an efficient, scalable NK workflow is key to staying at the forefront of this evolving field. Join this workshop to learn about STEMCELL’s NK cell isolation and expansion products. This workshop also features the Easy 250 EasySep™ Magnet, a new scalable and efficient system for manual column-free isolation. These next-generation tools enable researchers to streamline and accelerate their NK cell research.
This event is part of the STEMCELL Seminar Series and was recorded in our Cambridge, UK office. By inviting local scientists to attend talks from leading researchers, the STEMCELL Seminar Series helps scientists keep current with cutting edge technologies and innovations in their field.
Nature Research Round Table: Human Pluripotent Stem Cell Lines as Disease Models
Dr. Christine Mummery from the Leiden University Medical Center discusses the use of human pluripotent stem cells (hPSCs) for disease modeling and what standards are required; including for genome integrity, routine checks, and journal requirements.
This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here.
Note: Some original data from this presentation has been omitted to abide by copyright rules.