Studying Cystic Fibrosis Using Primary Human Nasal Epithelial Cells
Cystic Fibrosis (CF) is a genetic disease that affects multiple organs in the body. The primary defects are in the airway and related to epithelial dysfunction. Technological advances have enabled researchers to study CF using specialized in vitro cell culture models to recapitulate the pseudostratified airway epithelium. In this webinar, Dr. Theo Moraes elaborates on the advantages of using nasal epithelial cell cultures to perform such studies and their implications for precision medicine in CF. He also discusses the Program for Individualized Cystic Fibrosis Therapy (CFIT)—a collaboration between CF Canada, SickKids Foundation, and The Hospital for Sick Children—and how it utilizes the nasal culture methodology to develop a nationally accessible resource and to accelerate the development of individualized therapies for CF patients.
Dr. Theo Moraes is a clinician and researcher at The Hospital for Sick Children and the SickKids Research Institute in Toronto, Canada.
Organoid Expert Panel
What could organoids do for your research? In this in-depth panel discussion, STEMCELL's organoid experts answer questions submitted by you. Topics include evaluating organoids as tissue and disease models, variability in organoid cultures, and future outlooks in translational and clinical applications.
Joo-Hyeon Lee, PhD
Dr. Joo-Hyeon Lee shares her work using pulmonary organoids to study the cellular interactions between adult stem cells and niche cells in the lung
Jason Spence
Dr. Jason Spence describes his work on developing organoid systems to investigate tissue development and the physiology of immature tissues
Qi Tan, PhD
Dr. Qi Tan describes his work studying how epithelial cells maintain lung epithelial-mesenchymal homeostasis and protect the lung from fibrosis
Bronchosphere Culture in PneumaCult™-ALI
Light microscope visualization showing a bronchosphere cultured in PneumaCult™-ALI and shows mucus in the lumen being swirled around by the beating of synchronized cilia lining the lumen of the bronchosphere
EasySep™小鼠TIL（CD45）正选试剂盒
Cellular Organization and Biology of the Respiratory System Overview of the organization and function of different parts of the respiratory system
Studying Cystic Fibrosis Using Primary Human Nasal Epithelial Cells Cystic Fibrosis (CF) is a genetic disease that affects multiple organs in the body. The primary defects are in the airway and related to epithelial dysfunction. Technological advances have enabled researchers to study CF using specialized in vitro cell culture models to recapitulate the pseudostratified airway epithelium. In this webinar, Dr. Theo Moraes elaborates on the advantages of using nasal epithelial cell cultures to perform such studies and their implications for precision medicine in CF. He also discusses the Program for Individualized Cystic Fibrosis Therapy (CFIT)—a collaboration between CF Canada, SickKids Foundation, and The Hospital for Sick Children—and how it utilizes the nasal culture methodology to develop a nationally accessible resource and to accelerate the development of individualized therapies for CF patients.
Organoid Expert Panel What could organoids do for your research? In this in-depth panel discussion, STEMCELL's organoid experts answer questions submitted by you. Topics include evaluating organoids as tissue and disease models, variability in organoid cultures, and future outlooks in translational and clinical applications.
How to Grow Cerebral Organoids from Human Pluripotent Stem Cells Guide for growing cerebral organoids, or brain organoids, from human pluripotent stem cells (hPSCs)
Joo-Hyeon Lee, PhD Dr. Joo-Hyeon Lee shares her work using pulmonary organoids to study the cellular interactions between adult stem cells and niche cells in the lung
Jason Spence Dr. Jason Spence describes his work on developing organoid systems to investigate tissue development and the physiology of immature tissues
Qi Tan, PhD Dr. Qi Tan describes his work studying how epithelial cells maintain lung epithelial-mesenchymal homeostasis and protect the lung from fibrosis
SnapShot: Growing Organoids from Stem Cells Key culture conditions and organoid-forming cells from a variety of epithelial tissues
Bronchosphere Culture in PneumaCult™-ALI Light microscope visualization showing a bronchosphere cultured in PneumaCult™-ALI and shows mucus in the lumen being swirled around by the beating of synchronized cilia lining the lumen of the bronchosphere
