David Knapp, PhD
Dr. David Knapp shares his work examining how growth factors affect the survival, proliferation, and maintenance of cells of the cord blood HSC compartment
Non-Viral CRISPR Knock-In Anti-B7-H3 CAR-T Cells Are Amenable for Treatment of Subtypes of Small Cell Lung Cancer
In this webinar, Scientist Vimal Keerthi discusses his work on identifying CD276 (B7-H3) overexpression in primary human SCLC and developing a non-viral CRISPR-Cas9 knock-in (CKI) based platform against B7-H3 to manufacture CAR T cells for the treatment of SCLC. He demonstrates the feasibility of this CAR T manufacturing platform and how this provides a blueprint for immediate clinical translation, overcoming the bottleneck of viral vector production.
“Printing Human Tissues” Featuring Dr. Anthony Atala
On this episode of the Stem Cell Podcast, Dr. Anthony Atala from the Wake Forest Institute for Regenerative Medicine discusses tissue engineering, vascularization, and prioritizing safety when studying lab-grown organs.
Nature Research Round Table: Standards for Pluripotent Stem Cell Banking
Dr. Glyn Stacey, Director of the International Stem Cell Banking Initiative (ISCBI), discusses standards for pluripotent stem cell (PSC) banking with a focus on scientific challenges for PSCs, standardization of ethics, the role of stem cell biobanks, and best practices for cell therapy. This presentation and the following Q&A session were moderated by Dr. Joanne Mountford from the University of Glasgow.
This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here.
“Translating Stem Cell Discoveries” Featuring Dr. Ilyas Singeç
On this episode of the Stem Cell Podcast, Dr. Ilyas Singeç from National Center for Advancing Translational Sciences discusses standardizing stem cell differentiation, high-throughput cell culture, personalized medicine, and the potential for biomanufacturing in space.
This panel discussion was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here.