Optimized Workflows for High-Efficiency Genome Editing in Stem and Primary Cell Types
CRISPR-Cas genome editing in cell culture systems is a powerful technique for disease modeling and the development of cellular therapies. Compared to work with immortalized cell lines, genome editing of stem and primary cells presents unique challenges, including issues related to efficient delivery and expression of CRISPR machinery, clonogenicity, and cytotoxicity. In this webinar, our in-house expert, Dr. Ashley Watson, discusses optimized workflows for CRISPR-Cas9 genome editing in human pluripotent stem cells and primary T cells.
David Knapp, PhD
Dr. David Knapp shares his work examining how growth factors affect the survival, proliferation, and maintenance of cells of the cord blood HSC compartment
“Laser-Based Cell Manipulation” Featuring Dr. Marinna Madrid
On this episode of the Stem Cell Podcast, Dr. Marinna Madrid from Cellino discusses how lasers and image-guided machine learning can make iPSC-derived cell therapies viable at a large scale.
“Translating Stem Cell Discoveries” Featuring Dr. Ilyas Singeç
On this episode of the Stem Cell Podcast, Dr. Ilyas Singeç from National Center for Advancing Translational Sciences discusses standardizing stem cell differentiation, high-throughput cell culture, personalized medicine, and the potential for biomanufacturing in space.