Areas of Interest
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Predictive In Vitro Models for Toxicity Testing and Liver Research Having validated tools to perform predictive assays in a biologically-relevant system is key to success in drug discovery research. In this webinar, Dr. Terry Riss (Promega Corp) and Jennifer Christie (STEMCELL Technologies) discuss products and protocols that enable the incorporation of validated in vitro alternatives to animal models for toxicology studies. First, Dr. Riss presents in vitro assays for 3D cultures that monitor drug-induced cytotoxicity and explains how different assays can be multiplexed to measure multiple cell health parameters. Following this, Ms. Christie describes how to generate mature and functional hepatic organoids using HepatiCult™ and demonstrates their applications in liver research and hepatotoxicity assessment.
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“Manipulating Stem Cell Fate” Featuring Dr. Shuibing Chen On this episode of the Stem Cell Podcast, Dr. Shuibing Chen from Weill Cornell Medicine talks about using organoids to study diabetes, Zika, and SARS-CoV-2.
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“Neuronal Diversity” Featuring Dr. Paola Arlotta On this episode of the Stem Cell Podcast, Dr. Paola Arlotta from Harvard University talks about brain organoids as models for human development, neuropsychiatric disorders, and neurodegenerative diseases.
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“Neurodegenerative Diseases” Featuring Dr. Clive Svendsen On this episode of the Stem Cell Podcast, Dr. Clive Svendsen from Cedars-Sinai talks about using stem cells to model spinal muscular atrophy and the blood-brain barrier, and his cell-gene therapy trial for ALS.